Additional Information
Size:  | 
                                                    100 µl  | 
                                                
Target:  | 
                                                    Tau (pSer396)  | 
                                                
Conjugate:  | 
                                                    ATTO 390  | 
                                                
Research Area:  | 
                                                    Neuroscience | Neurodegeneration | Alzheimer's Disease | Tangles & Tau | Cell Signaling | Cytoskeleton | Microtubules | MT Associated Proteins | Neuroscience | Cell Markers | Neuron Markers | Axon Markers  | 
                                                
Alternative Name:  | 
                                                    Tau Antibody, Neurofibrillary tangle protein Antibody, MAPTL Antibody, Microtubule-associated protein tau Antibody, MTBT1 Antibody, Paired helical filament-tau Antibody, TAU Antibody, PHF-tau Antibody, MAPT Antibody, AI413597 antibody, AW045860 antib  | 
                                                
Category:  | 
                                                    Antibodies  | 
                                                
Product Type:  | 
                                                    Polyclonal Antibody  | 
                                                
Immunogen:  | 
                                                    Synthetic phospho-peptide from human Tau around the phosphorylation site of serine 396 (pSer396).  | 
                                                
Immunogen Species:  | 
                                                    Human  | 
                                                
Applications:  | 
                                                    WB, ELISA  | 
                                                
Host:  | 
                                                    Rabbit  | 
                                                
Isotype:  | 
                                                    IgG  | 
                                                
Species Reactivity:  | 
                                                    Human, Mouse, Rat  | 
                                                
Antibody Dilution:  | 
                                                    WB (1:250-500); ELISA (1:10000); optimal dilutions for assays should be determined by the user.  | 
                                                
Purification:  | 
                                                    Peptide Affinity Purified  | 
                                                
Storage Buffer:  | 
                                                    PBS, pH 7.4, 150mM NaCl, 50% glycerol, 0.02% sodium azide  | 
                                                
Concentration:  | 
                                                    N/A  | 
                                                
Specificity:  | 
                                                    Detects endogenous levels of Tau only when phosphorylated at serine 396 (pSer396).  | 
                                                
Storage:  | 
                                                    -20ºC  | 
                                                
Shipping:  | 
                                                    Blue Ice or 4ºC  | 
                                                
Certificate of Analysis:  | 
                                                    A 1:500 dilution of SPC-1436 was sufficient for detection of Tau (pSer396) in 10 µg of mouse brain cell lysates by ECL immunoblot analysis using goat anti-rabbit as the secondary antibody.  | 
                                                
Cellular Localization:  | 
                                                    Cytoskeleton, Plasma Membrane, Cell Membrane, Peripheral Membrane Protein, Cytoplasmic Side, Cytosol, Axon, Microtubule, Microtubule Associated Complex, Tubulin Complex, Nucleus, Nuclear Periphery, Nuclear Speck, Axolemma Plasma Membrane, Axolemma, C  | 
                                                
Tissue Specificity:  | 
                                                    Expressed in neurons. Isoform PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.  | 
                                                
Accession Number:  | 
                                                    NP_001116538.2  | 
                                                
Gene ID:  | 
                                                    4137  | 
                                                
Swiss-Prot:  | 
                                                    P10636  | 
                                                
Field of Use:  | 
                                                    For in vitro research use only.  |