TBX1 Polyclonal Antibody | E-AB-53339

TBX1 Polyclonal Antibody | E-AB-53339 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Brachyury, CAFS, CTHM, DGCR, DGS, DORV, T box, T box 1, T box 1 transcription factor, T box 1 transcription factor C, T box protein 1, T box transcription factor TBX 1, T box transcription factor TBX1, T-box protein 1, T-box transcription factor TBX1, TBX 1, TBX 1C, tbx1, TBX1, TBX1C, Testis specific T box protein, Testis-specific T-box protein, TGA, VCFS

Application: WB, IHC, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Epigenetics and Nuclear Signaling, Neuroscience

Background: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Concentration: 0.7 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human TBX1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 43 kDa

Molecular Weight(Observed): Refer to figures