TCF3 polyclonal Antibody | BS91323

TCF3 polyclonal Antibody | BS91323 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB FC

Application Range: WB:1:1,000 FC:1:50-1:100

Background: Differentiation of myogenic cells is regulated by multiple positively and negatively acting factors. One well characterized family of helix-loop-helix (HLH) proteins known to play an important role in the regulation of muscle cell development include Myo D, myogenin, Myf-5 and Myf-6 (also designated MRF-4 or herculin) . Myo D transcription factors form heterodimers with products of a more widely expressed family of bHLH genes, the E family, which consists of at least three distinct genes: E2A, IF2 and HEB. Myo D-E heterodimers bind avidly to consensus (CANNTG) E box target sites that are functionally important elements in the upstream regulatory sequences of many muscle-specific terminal differentiation genes. Both homo- and heterooligomers of these proteins are able to distinguish very closely related E box proteins and are believed to play important roles in lineage specific gene expression.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: TCF3 polyclonal Antibody detects endogenous levels of TCF3 protein.

Molecular Weight: 67 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: bHLHb21, TCF-3, TCF3, AGM8, bHLHb21, Class B basic helix-loop-helix protein 21, E12, E2A, E2A immunoglobulin enhancer binding factors E12/E47, E47, Helix loop helix protein HE47, Immunoglobulin enhancer-binding factor E12/E47, Immunoglobulin transcription factor 1, ITF1, Kappa-E2-binding factor, MGC129647, MGC129648, Negative vitamin D response element binding protein, NOL1-TCF3 fusion, TCF-3, Tcf3, TFE2, transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47), Transcription factor 3, transcription factor 3 variant 3, Transcription factor E2-alpha, Transcription factor ITF-1, VDIR, VDR interacting repressor, vitamin D receptor-interacting repressor,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: