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TCL1B polyclonal Antibody | BS72241
- SKU:
- BW-BS72241
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- Usually ships in 5 working days
Description
TCL1B polyclonal Antibody | BS72241 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human
Application: WB,IF
Application Range: WB 1:500 - 1:2000 IF 1:50 - 1:200
Background: T cell leukemia/lymphoma protein 1B (TCL-1B), also designated TML1, TCL/MTCP1-like 1, syncytiotrophoblast-specific protein and SYN-1, is involved in T cell prolymphocytic leukemia (T-PLL) . TCL-1B is located within the region on human chromosome 14q32.1 which, in T cell leukemias and lymphomasis, is frequently involved in chromosomal translocations and inversions with one of the T cell receptor loci. TCL-1B is activated by chromosomal rearrangements involving the TCL1 locus. In mouse, TCL-1B is represented by five homologues, TCL-1B1-TCL-1B5. The crystal structure of TCL-1B suggests that it may play a role in the transport of small molecules such as retinoids, nucleotides and fatty acids. TCL-1B is found in both the nucleus and the cytoplasm of normal bone marrow and peripheral lymphocytes.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: TCL1B polyclonal Antibody detects endogenous levels of TCL1B protein.
Molecular Weight: 15kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: SYN-1; TML1
Immunogen: Recombinant protein of human TCL1B
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: