TCP-1ζ polyclonal Antibody | BS5959

TCP-1ζ polyclonal Antibody | BS5959 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC

Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200

Background: The protein TCP-1 (t complex polypeptide 1) is a subunit of the heterooligomeric complex CCT (chaperonin containing TCP-1) present in the eukaryotic cytosol. The CCT of eukaryotic cytosol is composed of eight different subunit species, TCP-1 α, β, γ, δ, ε, ζ, η and θ, each encoded by a different gene. Two ζ subunits have been described: TCP-1 ζ (also designated TCP-1 ζ1) and TCP-1 ζ2. TCP-1 subunits are proposed to have independent functions in folding its in vivo substrates, the actins and tubulins. TCP-1 was first identified in the mouse as relevant for tail-less and embryonic lethal phenotypes. Sequences homologous to TCP-1 have been isolated in several other species, and the yeast TCP-1 has been shown to encode a molecular chaperone for Actin and Tubulin. TCP-1 found in mammalian cells and yeast plays an important role in the folding of cytosolic proteins.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: TCP-1ζ polyclonal Antibody detects endogenous levels of TCP-1ζ protein.

Molecular Weight: ~ 60 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: T-complex protein 1 subunit zeta; TCP-1-zeta; Acute morphine dependence-related protein 2; CCT-zeta-1; HTR3; Tcp20; CCT6A; CCT6; CCTZ; TCP1ζ; TCP 1ζ; TCP1-ζ; TCP-1-ζ; CCT-ζ-1; CCTζ-1; CCT-ζ1; CCTζ1;

Immunogen: Synthetic peptide, corresponding to amino acids 216-261 of Human TCP-1ζ.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: