LBD
TCPR1 Antibody (N-term) [APR05812G]
- SKU:
- LBD-APR05812G
- Availability:
- Usually ships in 5 working days
Description
TCPR1 Antibody (N-term) [APR05812G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This PALA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 162-189 amino acids from the N-terminal region of human TCPR1.
Cellular Localisation: Cytoplasmic vesicle, autophagosome membrane. Lysosome membrane. Note=Localizes to Lysosome membranes, and binds PtdIns (3) P at the surface of autophagosome. Localizes to autolysosomes, a vesicle formed by the fusion between autophagosomes and lysosomes
Molecular Weight: 129696
Clone: Polyclonal
Gene Name: TECPR1
Gene ID: 25851
Function: Tethering factor involved in autophagy. Involved in autophagosome maturation by promoting the autophagosome fusion with lysosomes: acts by associating with both the ATG5-ATG12 conjugate and phosphatidylinositol-3-phosphate (PtdIns (3) P) present at the surface of autophagosomes. Also involved in selective autophagy against bacterial pathogens, by being required for phagophore/preautophagosomal structure biogenesis and maturation.
Summary: N/A
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: IHC-P, WB, FC
Dilution: IHC-P--1:100~500 WB--1:1000 FC--1:10~50
Synonyms: Tectonin beta-propeller repeat-containing protein 1, TECPR1, KIAA1358