TCR gamma delta Antibody [UC7-13D5] | 98-892

TCR gamma delta Antibody [UC7-13D5] | 98-892 | Gentaur UK, US & Europe Distribution

Host: Hamster

Reactivity: Mouse

Homology: N/A

Immunogen: Mouse T cell clone G8

Research Area: Immunology, Stem Cell

Tested Application: Flow, IP

Application: TCR gamma delta Antibody [UC7-13D5] for use in flow cytometry, immunoprecipitation, costimulaton, and depletion assays.

Specificiy: TCRgammadelta

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: N/A

Clonality: Monoclonal

Clone: [UC7-13D5]

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

Concentration: 0.5 mg/mL

Storage Condition: Store vial at 2-8˚C

Alternate Name: N/A

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The TCRgammadelta heterodimer of the CD3/T cell receptor complex is clonotypic and consists of Ig-like variable and constant domains. It is expressed during thymopoiesis and on the small subpopulation of gammadelta TCR-expressing T lymphocytes in the periphery. The majority of T cells present in some epithelial tissues are gammadelta+ and have limited receptor diversity. The TCRgammadelta heterodimer recognizes peptide antigen bound to MHC antigens and subsequent signal transduction mediated by the invariant chains leads to T cell activation. The monoclonal antibody UC7-13D5 is specific for the gammadelta heterodimer and plate-bound UC7-13D5 activates gammadelta TCR-bearing cells. This antibody does not react with alphabeta TCR-expressing T cells.