TCS OX2 29 | B1838

TCS OX2 29 is a potent and selective OX2 (Orexin-2) receptor antagonist (IC₅₀ = 40 nM). Displays >250-fold selectivity for OX2 over OX1 (Orexin-1) and >50 receptors, ion channels and transporters.

TCS OX2 29 is a potent and selective OX2 (Orexin-2) receptor antagonist (IC₅₀ = 40 nM). Displays >250-fold selectivity for OX2 over OX1 (Orexin-1) and >50 receptors, ion channels and transporters.

B1838 | TCS OX2 29 DataSheet

Alternate Name/Synonyms: (2S)-1-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-3,3-dimethyl-2-[(4-pyridinylmethyl)amino]-1-butanone hydrochloride

Appearance: Pale yellow solid

Formulation: N/A

CAS Number: 372523-75-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: N/A

Molecular Formula: C₂₃H₃₁N₃O₃.HCl

Molecular Weight: 433.97

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: H₂O (>40 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: a potent and selective OX2 (Orexin-2) receptor antagonist

MDL Number: N/A

PubChem CID: 53302033

SMILES: CC(C)(C)C(C(=O)N1CCC2=CC(=C(C=C2C1)OC)OC)NCC3=CC=NC=C3.Cl

InChi: InChI=1S/C23H31N3O3.ClH/c1-23(2,3)21(25-14-16-6-9-24-10-7-16)22(27)26-11-8-17-12-19(28-4)20(29-5)13-18(17)15-26;/h6-7,9-10,12-13,21,25H,8,11,14-15H2,1-5H3;1H/t21-;/m1./s1

InChi Key: NHKNHFJTMINMBP-ZMBIFBSDSA-N