TCTEX1D4 Antibody | 6957

TCTEX1D4 Antibody | 6957 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: Predicted species reactivity based on immunogen sequence: Pig: (74%)

Immunogen: TCTEX1D4 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human TCTEX1D4.
The immunogen is located within the first 50 amino acids of TCTEX1D4.

Research Area: Signal Transduction

Tested Application: E, WB, IF

Application: TCTEX1D4 antibody can be used for detection of TCTEX1D4 by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Specificiy: TCTEX1D4 is predicted to not cross-react with other members of the TCTEX-type family.

Positive Control 1: Cat. No. 1404 - Mouse Liver Tissue Lysate

Positive Control 2: Cat. No. 10-201 - Human Liver Tissue Slide

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 24 kDa

Validation: N/A

Isoform: N/A

Purification: TCTEX1D4 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: TCTEX1D4 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: TCTEX1D4 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: TCTEX1D4 Antibody: Tctex1 domain-containing protein 4, Tctex-2-beta

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: TCTEX1D4 Antibody: Dyneins are multi-subunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal Dynein is an approximately 12 subunit complex of two heavy chains, two intermediate chains to anchor Dynein to its cargo, four smaller intermediate chains and several light chains. It performs functions necessary for cell survival such as organelle transport and centrosome assembly. TCTEX1 is a cytoplasmic dynein light chain found in a complex with Na+ CP type X (SCN10A) . TCTEX1D4, also called TCTEX2 beta, interacts with different members of the TGF-beta receptor family, and when overexpressed, inhibits TGF-beta signaling.