TdT Antibody| F41538-0.08ML/F41538-0.4ML/R31581/RQ5034/V8399-20UG

TdT Antibody| F41538-0.08ML/F41538-0.4ML/R31581/RQ5034/V8399-20UG | Gentaur UK, US & Europe Distribution

Background: This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: Mouse

Application: WB, ELISA

Application Details: Western blot: 1:1000

Application Note: Titration of the TdT antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This TdT antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 438-467 from human DNA nucleotidylexotransferase was used as the immunogen for this TdT antibody.

Storage: Aliquot the TdT antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A