CD1c Antibody| F42959-0.08ML/F42959-0.4ML/RQ4079/V8194-20UG

CD1c Antibody| F42959-0.08ML/F42959-0.4ML/RQ4079/V8194-20UG | Gentaur UK, US & Europe Distribution

Background: This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known.

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: N/A

Application: WB, ELISA

Application Details: Western blot: 1:1000

Application Note: Titration of the CD1c antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This CD1c antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 226-253 from the human protein was used as the immunogen for this CD1c antibody.

Storage: Aliquot the CD1c antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A