PRMT6 Antibody| F40469-0.08ML/F40469-0.4ML/R33955-100UG/V9235-20UG

PRMT6 Antibody| F40469-0.08ML/F40469-0.4ML/R33955-100UG/V9235-20UG | Gentaur UK, US & Europe Distribution

Background: Arginine methylation is an irreversible post translational modification which has only recently been linked to protein activity. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These protein include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins. The mammalian PRMT family currently consists of 7 members that share two large domains of homology. Outside of these domains, epitopes were identified and antibodies against all 7 PRMT members have been developed.

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: N/A

Application: IHC, WB, ELISA

Application Details: IHC (Paraffin): 1:50-1:100, Western blot: 1:1000

Application Note: Titration of the PRMT6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This PRMT6 antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 19-48 from the human protein was used as the immunogen for this PRMT6 antibody.

Storage: Aliquot the PRMT6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A