TEF-5 polyclonal Antibody | BS8914

TEF-5 polyclonal Antibody | BS8914 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse

Application: WB IHC IF

Application Range: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Background: The transcriptional enhancer factor (TEF) /TEAD family of proteins includes TEF-1, TEF-3, TEF-4 and TEF-5, all of which share a highly conserved 68 amino acid TEA/ATTS DNA-binding domain. TEF-5 (transcriptional enhancer factor-5), also known as TEAD3, TEAD5, DTEF-1 or ETFR-1, is a 435 amino acid nuclear protein that contains one TEA DNA-binding domain and belongs to the TEF transcriptional enhancer family. Expressed predominately in placental tissue and skeletal muscle, TEF-5 binds to multiple sites in the promotor of Placental lactogen II (also known as chorionic somatomammotropin-B) and, via this binding, enhances Placental lactogen II transcription. Due to its ability to enhance the expression of placenta-related genes, TEF-5 is thought to function as an important regulatory protein within the human placenta.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: TEF-5 polyclonal Antibody detects endogenous levels of TEF-5 protein.

Molecular Weight: ~ 49kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Transcriptional enhancer factor TEF-5; DTEF-1; TEA domain family member 3; TEAD-3; TEAD3; TEAD5; TEF5

Immunogen: Recombinant full length Human TEF-5.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: