26
Temsirolimus (CCI-779, Torisel) | 1600
- SKU:
- 26-1600-GEN
- Availability:
- Usually shipped in 5 working days
Description
mTOR inhibitor with anti-cancer activity. It has anti-angiogenic effects which may contribute to the antitumor activity of temsirolimus observed in breast cancer. Temsirolimus shows synergistic in vivo anti-myeloma effects in combination with dexamethasone in a xenograft model.
Temsirolimus (CCI-779, Torisel) is an mTOR inhibitor with anti-cancer activity. It has anti-angiogenic effects which may contribute to the antitumor activity of temsirolimus observed in breast cancer.
1600 | Temsirolimus (CCI-779, Torisel) DataSheet
Alternate Name/Synonyms: CCI-779,Torisel
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 162635-04-3
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₅₆H₈₇NO₁₆
Molecular Weight: 1030.29
Cell-Permeable?: Yes
Purity: ≥99%
Solubilities: DMSO (200 mg/ml)
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: A mTOR inhibitor
MDL Number: MFCD00934421
PubChem CID: 6918289
SMILES: CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O) C1(O2)O)C(C)CC4CCC(C(C4)OC)OC(=O)C(C)(CO)CO)C)C)O)OC)C)C)C)OC
InChi: InChI=1S/C56H87NO16/c1-33-17-13-12-14-18-34(2)45(68-9)29-41-22-20-39(7) 56(67,73-41)51(63)52(64)57-24-16-15-19-42(57)53(65)71-46(30-43(60)35(3)26-38 (6)49(62)50(70-11)48(61)37(5)25-33)36(4)27-40-21-23-44(47(28-40)69-10) 72-54(66)55(8,31-58)32-59/h12-14,17-18,26,33,35-37,39-42,44-47,49-50, 58-59,62,67H,15-16,19-25,27-32H2,1-11H3/b14-12+,17-13+,34-18+, 38-26+/t33-,35-,36-,37-,39-,40+,41+,42+,44-,45+,46+,47-,49-,50+, 56-/m1/s1
InChi Key: CBPNZQVSJQDFBE-FUXHJELOSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
24months |