Teneligliptin | B1932

Teneligliptin is a potent DPP-4 (dipeptidylpeptidase-4) inhibitor, that competitively inhibits human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC₅₀s of approximately 1 nM. Useful drug for treatment of type 2 diabetes mellitus (T2DM).

Teneligliptin is a potent DPP-4 (dipeptidylpeptidase-4) inhibitor, that competitively inhibits human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC₅₀s of approximately 1 nM. Useful drug for treatment of type 2 diabetes mellitus (T2DM).

B1932 | Teneligliptin DataSheet

Alternate Name/Synonyms: ((2S,4S)-4-(4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl)pyrrolidin-2-yl)(thiazolidin-3-yl)methanone; Tenelia

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 760937-92-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₂H₃₀N6₆OS

Molecular Weight: 426.58

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (~10 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent DPP-4 (dipeptidylpeptidase-4) inhibitor

MDL Number: N/A

PubChem CID: 11949652

SMILES: CC1=NN(C(=C1)N2CCN(CC2)C3CC(NC3)C(=O)N4CCSC4)C5=CC=CC=C5

InChi: InChI=1S/C22H30N6OS/c1-17-13-21(28(24-17)18-5-3-2-4-6-18)26-9-7-25(8-10-26)19-14-20(23-15-19)22(29)27-11-12-30-16-27/h2-6,13,19-20,23H,7-12,14-16H2,1H3/t19-,20-/m0/s1

InChi Key: WGRQANOPCQRCME-PMACEKPBSA-N