TENM3 Antibody | 8151

TENM3 Antibody | 8151 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: TENM3 antibody was raised against a 17 amino acid peptide near the amino terminus of human TENM3.
The immunogen is located within the first 50 amino acids of TENM3.

Research Area: Stem Cell, Neuroscience

Tested Application: E, WB, IHC-P, IF

Application: TENM3 antibody can be used for detection of TENM3 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Specificiy: TENM3 antibody is human, mouse and rat reactive. TENM3 antibody is predicted to not cross-react with other members of the TENM family.

Positive Control 1: Cat. No. 1210 - HEK293 Cell Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 297 kDa
Observed: 300 kDa

Validation: N/A

Isoform: N/A

Purification: TENM3 antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: TENM3 antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: TENM3 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: Teneurin transmembrane protein 3, teneurin-3, ODZ3, TEN-M3, TNM3, MCOPCB9

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The teneurin transmembrane protein 3 (TENM3) is a member of a family of four neuronal cell surface proteins homologous to the Drosophila pair-rule gene Ten-m (1, 2) . TENM3 is expressed in cartilaginous cells during postnatal growth in mice (3) , as well as the adult eye and optic stalk (4) . Homozygous null mutations in TENM3 causes microphthalmia in humans (5) .