Description
TES polyclonal Antibody | BS72943 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human
Application: WB,IHC
Application Range: WB 1:2000 - 1:5000 IHC 1:50 - 1:200
Background: Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. This protein is a negative regulator of cell growth and may act as a tumor suppressor. This scaffold protein may also play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Multiple protein isoforms are encoded by transcript variants of this gene.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: TES polyclonal Antibody detects endogenous levels of TES protein.
Molecular Weight: Refer to figures
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: TESS;TESS-2
Immunogen: Recombinant protein of human TES
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: Contribution of Soluble Factors to EMT,