TEX2 Antibody (Center) [APR04262G]

TEX2 Antibody (Center) [APR04262G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This TEX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 571-599 amino acids from the Central region of human TEX2.

Cellular Localisation: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q06833}; Multi-pass membrane protein. Nucleus membrane {ECO:0000250|UniProtKB:Q06833}; Multi- pass membrane protein. Note=Enriched at the nucleus- vacuole junction (PubMed:22250200) . During endoplasmic reticulum (ER) stress, localizes to ER-Golgi contacts (By similarity) {ECO:0000250|UniProtKB:Q06833, ECO:0000269|PubMed:22250200}

Molecular Weight: 125303

Clone: Polyclonal

Gene Name: TEX2

Gene ID: 55852

Function: During endoplasmic reticulum (ER) stress or when cellular ceramide levels increase, may induce contacts between the ER and medial-Golgi complex to facilitate non-vesicular transport of ceramides from the ER to the Golgi complex where they are converted to complex sphingolipids, preventing toxic ceramide accumulation.

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Testis-expressed sequence 2 protein, Transmembrane protein 96, TEX2, KIAA1738, TMEM96