TGFBR1 Polyclonal Antibody | E-AB-40428

TGFBR1 Polyclonal Antibody | E-AB-40428 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: AAT5, Activin A receptor type II like kinase, Activin receptor like kinase 5, ACVRLK4, ALK5, LDS1A, LDS2A, MSSE, SKR4, TGF beta receptor type 1, TGFBR1 protein, TGFR1, Transforming growth factor beta receptor 1

Application: WB, IHC

Reactivity: Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cardiovascular, Signal Transduction, Stem Cells, Cancer, Metabolism

Background: The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant Rat TGF-beta receptor type-1 protein

Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3

Purification Method: Antigen Affinity Purification

Dilution: WB 1:500-1:2000 IHC 1:100-1:300

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 56 kDa

Molecular Weight(Observed): 56 kDa