TGR5-Receptor-Agonist | B1635

TGR5 Receptor Agonist, a potent TGR5(GPCR19) agonist, showed improved potency in the U2-OS cell assay (pEC50 = 6.8) and in melanophore cells (pEC50 = 7.5).

TGR5 Receptor Agonist, a potent TGR5(GPCR19) agonist, showed improved potency in the U2-OS cell assay (pEC50 = 6.8) and in melanophore cells (pEC50 = 7.5).

B1635 | TGR5-Receptor-Agonist DataSheet

Alternate Name/Synonyms: TGR5-Receptor-Agonist; TGR5; 3-(2-chlorophenyl)-N-(4-chlorophenyl)-N,5-dimethyl-4-isoxazolecarboxamide; MDK00245; MDK-00245; MDK 00245

Appearance: Solid

Formulation: N/A

CAS Number: 1197300-24-5

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₈H₁₄Cl₂N₂O₂

Molecular Weight: 361.22

Cell-Permeable?: Yes

Purity: >98%

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent TGR5 G-protein receptor (GPCR19) agonist

MDL Number: NA

PubChem CID: 44605616

SMILES: CC1=C(C(=NO1)C2=CC=CC=C2Cl)C(=O)N(C)C3=CC=C(C=C3)Cl

InChi: 1S/C18H14Cl2N2O2/c1-11-16(17(21-24-11)14-5-3-4-6-15(14)20)18(23)22(2)13-9-7-12(19)8-10-13/h3-10H,1-2H3

InChi Key: IGRCWJPBLWGNPX-UHFFFAOYSA-N