TGX-155 | B2917

TGX-155 is an inhibitor of phosphoinositide 3-kinase (PI3K). PI3Ks and their lipid product phosphatidylinositol-3,4,5-trisphosphate are involved in signaling events in many cellular processes. TGX-155 selectively inhibits the p110β catalytic subunit of Class I PI3K with an IC₅₀ of 30 nM in vitro.

TGX-155 is an inhibitor of phosphoinositide 3-kinase (PI3K). PI3Ks and their lipid product phosphatidylinositol-3,4,5-trisphosphate are involved in signaling events in many cellular processes. TGX-155 selectively inhibits the p110β catalytic subunit of Class I PI3K with an IC₅₀ of 30 nM in vitro.

B2917 | TGX-155 DataSheet

Alternate Name/Synonyms: 8-(4-Fluoro-2-methylphenoxy)-2-(4-morpholinyl)-4(1H)-quinolinone

Appearance: Solid

Formulation:

CAS Number: 351071-90-4

Structure Available?: True

Peptide sequence:

Salt Form: false

Molecular Formula: C₂₀H₁₉FN₂O₃

Molecular Weight: 354.37

Cell-Permeable?: True

Purity: 95%

Solubilities: Soluble in DMSO in 0

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: An inhibitor of PI3K

MDL Number:

PubChem CID: 16757579

SMILES: CC1=C(C=CC(=C1)F)OC2=CC=CC3=C2NC(=CC3=O)N4CCOCC4

InChi: InChI=1S/C20H19FN2O3/c1-13-11-14(21)5-6-17(13)26-18-4-2-3-15-16(24)12-19(22-20(15)18)23-7-9-25-10-8-23/h2-6,11-12H,7-10H2,1H3,(H,22,24)

InChi Key: