Description
THG1L Polyclonal Antibody | E-AB-19210 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: ICF45, Interphase cytoplasmic foci protein 45, Probable tRNA(His) guanylyltransferase, THG1, THG1L, tRNA histidine guanylyltransferase 1 like (S. cerevisiae), tRNA-histidine guanylyltransferase
Application: IHC, ELISA
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cell Biology
Background: The protein encoded by this gene is a mitochondrial protein that is induced by high levels of glucose and is associated with diabetic nephropathy. The encoded protein appears to increase mitochondrial biogenesis, which could lead to renal fibrosis. Another function of this protein is that of a guanyltransferase, adding GMP to the 5' end of tRNA(His). Several transcript variants encoding different isoforms have been found for this gene.
Concentration: 1.26 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Fusion protein of human THG1L
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: IHC 1:50-1:200, ELISA 1:5000-1:10000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): N/A