Thrombomodulin polyclonal Antibody | BS5650

Thrombomodulin polyclonal Antibody | BS5650 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: Thrombomodulin (TM), also called CD141, is a type I membrane receptor that is specific to endothelial cells. TM has a cysteine-rich extracellular domain with six EGF-like regions. It forms a complex with Thrombin, which activates Protein C to generate activated Protein C (APC), an anticoagulant enzyme. APC together with Protein S inhibits coagulation by inactivating Factors Va and VIIIa. Deletion of the TM gene results in embryonic lethality in mice.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Thrombomodulin polyclonal Antibody detects endogenous levels of Thrombomodulin protein.

Molecular Weight: ~ 60, 105 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Thrombomodulin; TM; Fetomodulin; CD141; THBD; THRM

Immunogen: Synthetic peptide, corresponding to amino acids 530-575 of Human Thrombomodulin.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: