Thrombomodulin polyclonal Antibody | BS91345

Thrombomodulin polyclonal Antibody | BS91345 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB IHC IP

Application Range: WB:1:500-1:2,000 IHC:1:50-1:200 IP:1:10-1:50

Background: Thrombomodulin (TM), also called CD141, is a type I membrane receptor that is specific to endothelial cells. TM has a cysteine-rich extracellular domain with six EGF-like regions. It forms a complex with Thrombin, which activates Protein C to generate activated Protein C (APC), an anticoagulant enzyme. APC together with Protein S inhibits coagulation by inactivating Factors Va and VIIIa. Deletion of the TM gene results in embryonic lethality in mice.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: Thrombomodulin polyclonal Antibody detects endogenous levels of Thrombomodulin protein.

Molecular Weight: 100 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: TM, THBD, THRM, AHUS 6, AHUS6, BDCA 3, BDCA3, CD 141, CD141, CD141 antigen, Fetomodulin, Thbd, THPH12, THRM, Thrombomodulin, TM, TRBM,

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: