TIEG2 Antibody (N-term) [APR05776G]

TIEG2 Antibody (N-term) [APR05776G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This TIEG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-36 amino acids from the N-terminal region of human TIEG2.

Cellular Localisation: Nucleus.

Molecular Weight: 55139

Clone: Polyclonal

Gene Name: KLF11

Gene ID: 8462

Function: Transcription factor (PubMed:9748269, PubMed:10207080) . Activates the epsilon- and gamma-globin gene promoters and, to a much lower degree, the beta-globin gene and represses promoters containing SP1-like binding inhibiting cell growth (PubMed:9748269, PubMed:10207080, PubMed:16131492) . Represses transcription of SMAD7 which enhances TGF-beta signaling (By similarity) . Induces apoptosis (By similarity) .

Summary: Tissue Location: Ubiquitous. Higher expression in erythroid cells.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: IHC-P, FC, IF, WB

Dilution: WB--1:1000 IHC-P--1:100~500 FC--1:10~50 IF--1:10~50

Synonyms: Krueppel-like factor 11, Transforming growth factor-beta-inducible early growth response protein 2, TGFB-inducible early growth response protein 2, TIEG-2, KLF11, FKLF, TIEG2