LBD
TIGIT Antibody (C-term) [APR30643G]
- SKU:
- LBD-APR30643G
- Availability:
- Usually ships in 5 working days
Description
TIGIT Antibody (C-term) [APR30643G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H, M
Specificity: This TIGIT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-233 amino acids from the C-terminal region of human TIGIT.
Cellular Localisation: Cell membrane; Single-pass type I membrane protein
Molecular Weight: 26319
Clone: Polyclonal
Gene Name: TIGIT
Gene ID: 201633
Function: Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.
Summary: Tissue Location: Expressed at low levels on peripheral memory and regulatory CD4+ T-cells and NK cells and is up-regulated following activation of these cells (at protein level)
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB, FC
Dilution: WB--1:1000 FC--1:10~50
Synonyms: T-cell immunoreceptor with Ig and ITIM domains, V-set and immunoglobulin domain-containing protein 9, V-set and transmembrane domain-containing protein 3, TIGIT, VSIG9, VSTM3