Description
TIMM8A Polyclonal Antibody | E-AB-18755 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: DDP 1, DDP, DDP1, Deafness dystonia protein 1, Deafness/dystonia peptide, DFN 1, DFN1, MGC12262, Mitochondrial import inner membrane translocase subunit Tim8 A, MTS, TIM 8A, TIM8, TIM8A, TIM8A, TIMM 8A, timm8a, Translocase of inner mitochondrial membrane 8 homolog A, X linked deafness dystonia protein, X-linked deafness dystonia protein
Application: IHC, ELISA
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Neuroscience, Signal transduction
Background: This translocase is involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The gene is mutated in Mohr-Tranebjaerg syndrome/Deafness Dystonia Syndrome (MTS/DDS) and it is postulated that MTS/DDS is a mitochondrial disease caused by a defective mitochondrial protein import system. Defects in this gene also cause Jensen syndrome; an X-linked disease with opticoacoustic nerve atrophy and muscle weakness. This protein, along with TIMM13, forms a 70 kDa heterohexamer. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Concentration: 0.84 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Fusion protein of human TIMM8A
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: IHC 1:40-1:200, ELISA 1:5000-1:10000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): N/A