TIMP1 Polyclonal Antibody | E-AB-40310

TIMP1 Polyclonal Antibody | E-AB-40310 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Clgi, Collagenase inhibitor, Collagenase inhibitor, Human, EPA, EPO, Erythroid Potentiating Activity, Erythroid-potentiating activity, Fibroblast collagenase inhibitor, FLJ90373, HCI, Human Collagenase Inhibitor, Metalloproteinase inhibitor 1, Metalloproteinase inhibitor 1 precursor, OTTHUMP00000023214, TIMP 1, TIMP, TIMP metallopeptidase inhibitor 1, TIMP-1, Timp1, TIMP1 protein, TIMP1, Tissue Inhibitor of Metalloproteinase 1, Tissue inhibitor of metalloproteinases 1, Tissue inhibitor of metalloproteinases, Ttissue inhibitor of metalloproteinase 1 erythroid potentiating activity collagenase inhibitor

Application: IHC

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cell Biology, Cardiovascular, Signal Transduction

Background: This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant Mouse Metalloproteinase inhibitor 1 protein

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Purification Method: Antigen Affinity Purification

Dilution: IHC 1:100-1:300

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A