BW
Tissue Factor polyclonal Antibody | BS91349
- SKU:
- BW-BS91349
- Availability:
- Usually ships in 5 working days
Description
Tissue Factor polyclonal Antibody | BS91349 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse, Rat
Application: WB ICC/IF IHC
Application Range: WB:1:1,000-1:5,000 ICC:1:100-1:500 IHC:1:100-1:500
Background: Hemostasis following tissue injury involves the deployment of essential plasma procoagulants (Prothrombin and Factors X, IX, V and VIII), which are involved in a blood coagulation cascade leading to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Coagulation Factor V (Factor V, FV, proaccelerin, labile factor) is a 2196 amino acid, single chain glycoprotein that is cleaved by Thrombin to yield an active, Ca2+-dependent dimer that is essential to the blood coagulation cascade. Together with catalytic Factor Xa and Ca2+ on the surface of platelets or endothelial cells, Factor Va coordinates into a Prothrombinase complex, which mediates proteolysis of Prothrombin into active Thrombin. Tissue factor (TF), also designated coagulation Factor III is a cell surface glycoprotein that enables cells to initiate blood coagulation cascades. It functions as a high-affinity receptor for coagulation Factor VII.
Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: Tissue Factor polyclonal Antibody detects endogenous levels of Tissue Factor protein.
Molecular Weight: 50 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: TF, F3, CD142, CD142 antigen, Coagulation factor III (thromboplastin tissue factor), Coagulation factor III, F3, FLJ17960, TF, TF, TFA, Thromboplastin, Tissue factor,
Immunogen: recombinant protein
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: ProA affinity purified
Pathway: