TKT polyclonal Antibody | BS8124

TKT polyclonal Antibody | BS8124 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: IHC

Application Range: WB: 1:500~1:2000 IHC: 1:50~1:200

Background: Transketolase (TK or TKT), a member of the Transketolase family, is a multifunctional protein that plays a role in diabetes, cancer, Alzheimer’s disease and Wernicke-Korsakoff’s syndrome, a latent genetic neurological disorder. Transketolase is also important for the prevention of hyperglycemia-induced vascular damage. Transketolase is a crucial protein in the pentose phosphate pathway (PPP), where it catalyzes several reactions. In combination with Transaldolase, Transketolase functions as a link between glycolysis and the non-oxidative part of the PPP, allowing the cell to adapt to varying metabolic conditions in response to environmental changes. Transketolase activity is detected in small intestine epithelia, liver parenchyma, tongue, cornea and trachea. It is also expressed in the proximal tubules of kidney and in ganglion cells in medulla of the adrenal gland.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: TKT polyclonal Antibody detects endogenous levels of TKT protein.

Molecular Weight: Refer to figures

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Transketolase;TX; TKT

Immunogen: Recombinant full length Human TKT.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: