TLR7 Antibody| F43188-0.08ML/F43188-0.4ML/F54019-0.1ML/R30823

TLR7 Antibody| F43188-0.08ML/F43188-0.4ML/F54019-0.1ML/R30823 | Gentaur UK, US & Europe Distribution

Background: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X.

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: Mouse

Application: WB, ELISA

Application Details: Western blot: 1:1000

Application Note: Titration of the TLR7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This TLR7 antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 899-926 from the human protein was used as the immunogen for this TLR7 antibody.

Storage: Aliquot the TLR7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A