TMED10 polyclonal Antibody | BS8426

TMED10 polyclonal Antibody | BS8426 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC IF

Application Range: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Background: TMP21 (21 kDa transmembrane-trafficking protein), also known as TMED10 (transmembrane emp24 domain-containing protein 10), Tmp-21, S31I125, S31III125, p23 or p24∂, is a member of the EMP24/GP25L/p24 cargo family of proteins that regulates vesicular trafficking in the early secretory pathway. TMP21 is a ubiquitously expressed single-pass type I membrane protein localizing to the Golgi cisternae and the plasma membrane. It contains one GOLD (Golgi dynamics) domain and participates in protein transport and quality control between the endoplasmic reticulum (ER) and the Golgi complex. In addition, TMP21 is a component of the heteromeric secretase complex (or Presenilin complex) and functions to regulate the ©-secretase activity. Two isoforms, namely TMP21-I and TMP21-II, exist for this protein.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: TMED10 polyclonal Antibody detects endogenous levels of TMED10 protein.

Molecular Weight: ~ 25 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Transmembrane emp24 domain-containing protein 10; 21 kDa transmembrane-trafficking protein; S31III125; S31I125; Tmp-21-I; Transmembrane protein Tmp21; p23; p24 family protein delta-1; p24delta1; p24delta; TMED10; TMP21

Immunogen: Recombinant full length Human TMED10.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: