TMEM173 Antibody | 26-276

TMEM173 Antibody | 26-276 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Homology: N/A

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TMEM173.

Research Area: Other

Tested Application: E, WB

Application: TMEM173 antibody can be used for detection of TMEM173 by ELISA at 1:62500. TMEM173 antibody can be used for detection of TMEM173 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000.

Specificiy: N/A

Positive Control 1: Cat. No. 1201 - HeLa Cell Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 42 kDa

Validation: N/A

Isoform: N/A

Purification: Antibody is purified by peptide affinity chromatography method.

Clonality: Polyclonal

Clone: N/A

Isotype: N/A

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Concentration: batch dependent

Storage Condition: For short periods of storage (days) store at 4˚C. For longer periods of storage, store TMEM173 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Alternate Name: TMEM173, FLJ38577, ERIS, MITA, MPYS, NET23, STING

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: TMEM173 acts as a facilitator of innate immune signaling. It is able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon (IFN-alpha and IFN-beta) and exert a potent anti-viral state following expression. TMEM173 may be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons.It also may be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II) . TMEM173 mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.