TMOD4 Antibody (Center) [AMM08247G]

TMOD4 Antibody (Center) [AMM08247G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This TMOD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-176 amino acids from the Central region of human TMOD4.

Cellular Localisation: Cytoplasm, cytoskeleton. Note=In myofibrils with sarcomeric structure, localizes to the pointed end of actin thin filaments (PubMed:25250574) .

Molecular Weight: 39335

Clone: Polyclonal

Gene Name: TMOD4

Gene ID: 29765

Function: Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton.

Summary: Tissue Location: Highly expressed in skeletal muscle.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Tropomodulin-4, Skeletal muscle tropomodulin, Sk-Tmod, TMOD4