TMPRSS11A polyclonal Antibody | BS71307

TMPRSS11A polyclonal Antibody | BS71307 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB 1:500 - 1:2000

Background: TMPRSS11A (transmembrane protease serine 11A), also known as ECRG1 (esophageal cancer-susceptibility gene 1 protein), HATL1 (airway trypsin-like protease 1) or HESP (epidermal type-II transmembrane serine protease), is a 421 amino acid single-pass type II membrane protein that belongs to the peptidase S1 family and exists as two alternatively spliced isoforms. TMPRSS11A contains one peptidase S1 domain, one SEA domain and may interact with Miz-1. As a probable serine protease, TMPRSS11A may play a role in cellular senescence. Over-expression of TMPRSS11A inhibits cell growth and induces G1 cell cycle arrest.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: TMPRSS11A polyclonal Antibody detects endogenous levels of TMPRSS11A protein.

Molecular Weight: ~ 48 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: TMPRSS11A; ECRG1; HATL1; HESP; Transmembrane protease serine 11A

Immunogen: Recombinant protein of human TMPRSS11A.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: