TMX3 Polyclonal Antibody | E-AB-19158

TMX3 Polyclonal Antibody | E-AB-19158 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: KIAA1830, PDIA13, Protein disulfide isomerase family A, member 13, Protein disulfide-isomerase TMX3, Thioredoxin domain containing 10, Thioredoxin domain-containing protein 10, Thioredoxin-related transmembrane protein 3, TMX3, TMX3, TXNDC10

Application: IHC, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cell Biology, Metabolism, Signal transduction

Background: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The canonical protein encoded by this gene has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and a C-terminal ER-retention sequence. This gene is expressed in many tissues but has its highest expression in heart and skeletal muscle. It is expressed in the retinal neuroepithelium and lens epithelium in the developing murine eye and haploinsufficiency of this gene in humans and zebrafish is associated with microphthalmia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Concentration: 1.26 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human TMX3

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:50-1:200, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A