TNF-IP 1 (S122) polyclonal Antibody | BS2484

TNF-IP 1 (S122) polyclonal Antibody | BS2484 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC

Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200

Background: TNFα-IP 1 (tumor necrosis factor, α-induced protein 1, endothelial), also known as B12, B61, EDP1 or TNFAIP1, is a BTB/POZ domain-containing protein that belongs to the KCTD10/KCTD13/TNFAIP1 family. TNFα-IP 1 contains one BTB/POZ motif, which is known to mediate homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. The expression of TNFα-IP 1 can be induced by IL-6 and by TNFα in the umbilical vein of endothelial cells. TNFα-IP 1 may be involved in DNA repair, DNA synthesis, cell apoptosis and human diseases. TNFα-IP 1 is suggested to play a role in the process of cancer and in the innate immunity against the Hepatitis B virus.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: TNF-IP 1 (S122) polyclonal Antibody detects endogenous levels of TNF-IP 1 protein.

Molecular Weight: ~ 36 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2; hBACURD2; BTB/POZ domain-containing protein TNFAIP1; Protein B12; Tumor necrosis factor, alpha-induced protein 1, endothelial; TNFAIP1; BACURD2; EDP1

Immunogen: Synthetic peptide, corresponding to amino acids 90-140 of Human TNF-IP 1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: