BW
TNFRSF1B polyclonal Antibody | BS6148
- SKU:
- BW-BS6148
- Availability:
- Usually ships in 5 working days
Description
TNFRSF1B polyclonal Antibody | BS6148 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB
Application Range: WB 1:500 - 1:2000
Background: Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: TNFRSF1B polyclonal Antibody detects endogenous levels of TNFRSF1B protein.
Molecular Weight: ~ 64 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Tumor necrosis factor receptor superfamily member 1B; Tumor necrosis factor receptor 2; TNF-R2; Tumor necrosis factor receptor type II; TNF-RII; TNFR-II; p75; p80 TNF-alpha receptor; CD120b; INN=Etanercept; Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2; TBP-2; TBPII; TNFRSF1B; TNFBR; TNFR2
Immunogen: Recombinant full length Human TNFRSF1B.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: Neuronal and Glial Cell Marker Atlas,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,