TNFRSF6B, human recombinant | 7329

TNFRSF6B belongs to Tumor necrosis factor receptor superfamily. It acts as a decoy receptor that competes with death receptors for ligand binding. This protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death and T cell activation as well as to induce angiogenesis via neutralization of TL1A. Recombinant human TNFRSF6B protein, fused to His-tag at N-terminus, was expressed in E.coli.

7329 | TNFRSF6B human recombinant DataSheet

Biomolecule/Target: TNFRSF6B

Synonyms: Tumor necrosis factor receptor superfamily member 6B

Alternates names: Tumor necrosis factor receptor superfamily member 6B

Taglines: Acts as a decoy receptor that competes with death receptors for ligand binding

NCBI Gene ID #: 7132

NCBI Gene Symbol: TNR1A

Gene Source: Human

Accession #: AAA36756

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: < 1.0 EU per 1 microgram of protein

Activity (Specifications/test method): N/A

Biological activity: The biological activity of sTNF-RI was determined by its inhibitory effect of the TNF- mediated cytotoxicity in murine L-929 cells. The ED for the effect in the presence of 0.25 ng/ml of recombinant TNF-, is 0.05 mg/ml.

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 32.1 kDa (294 aa, 30-300 aa + His Tag), confirmed by MALDI-TOF.

Concentration: 1 mg/ml

Appearance: Liquid

Physical form description: 1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol and 2 M Urea

Reconstitution Instructions: Reconstitute in 5 mM Tris, pH 8.0 to a concentration of 1 mg/ml. This solution can then be diluted into other aqueous buffers or stored at –4°C for 1 week or –20°C for future use.

Amino acid sequence: N/A