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TNFRSF6B, human recombinant | 7329
- SKU:
- 26-7329-GEN
- Availability:
- Usually shipped in 5 working days
Description
TNFRSF6B belongs to Tumor necrosis factor receptor superfamily. It acts as a decoy receptor that competes with death receptors for ligand binding. This protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death and T cell activation as well as to induce angiogenesis via neutralization of TL1A. Recombinant human TNFRSF6B protein, fused to His-tag at N-terminus, was expressed in E.coli.
7329 | TNFRSF6B human recombinant DataSheet
Biomolecule/Target: TNFRSF6B
Synonyms: Tumor necrosis factor receptor superfamily member 6B
Alternates names: Tumor necrosis factor receptor superfamily member 6B
Taglines: Acts as a decoy receptor that competes with death receptors for ligand binding
NCBI Gene ID #: 7132
NCBI Gene Symbol: TNR1A
Gene Source: Human
Accession #: AAA36756
Recombinant: Yes
Source: E. coli
Purity by SDS-PAGEs: 98%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: < 1.0 EU per 1 microgram of protein
Activity (Specifications/test method): N/A
Biological activity: The biological activity of sTNF-RI was determined by its inhibitory effect of the TNF- mediated cytotoxicity in murine L-929 cells. The ED for the effect in the presence of 0.25 ng/ml of recombinant TNF-, is 0.05 mg/ml.
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 32.1 kDa (294 aa, 30-300 aa + His Tag), confirmed by MALDI-TOF.
Concentration: 1 mg/ml
Appearance: Liquid
Physical form description: 1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol and 2 M Urea
Reconstitution Instructions: Reconstitute in 5 mM Tris, pH 8.0 to a concentration of 1 mg/ml. This solution can then be diluted into other aqueous buffers or stored at 4°C for 1 week or 20°C for future use.
Amino acid sequence: N/A