TNFSF14 Antibody | 18-439

TNFSF14 Antibody | 18-439 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant protein of human TNFSF14

Research Area: Chemokines & Cytokines, Immunology, Innate Immunity

Tested Application: WB

Application: WB: 1:1000 - 1:2000

Specificiy: N/A

Positive Control 1: Raji

Positive Control 2: LO2

Positive Control 3: A-549

Positive Control 4: 293T

Positive Control 5: THP-1

Positive Control 6: N/A

Molecular Weight: Observed: 30kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: tumor necrosis factor superfamily member LIGHT, tumor necrosis factor receptor-like 2, tumor necrosis factor ligand superfamily, member 14, ligand for herpesvirus entry mediator, herpesvirus entry mediator A, delta transmembrane LIGHT, TR2, LTg, LIGHT, HVEML, CD258, tumor necrosis factor (ligand) superfamily, TNFSF14, UNQ391/PRO726

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM) . This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported.