TNNI3 Polyclonal Antibody | E-AB-70275

TNNI3 Polyclonal Antibody | E-AB-70275 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: cardiac muscle, Cardiac troponin I, cardiomyopathy, dilated 2A (autosomal recessive), Cardiomyopathy, familial hypertrophic, 7, included, CMD1FF, CMD2A, CMH7, cTnI, Familial hypertrophic cardiomyopathy 7, MGC116817, RCM1, Tn1, Tni, TNN I3, TNNC 1, TNNC1, TNNI3, TNNI3, Troponin I, Troponin I cardiac, Troponin I cardiac muscle, Troponin I cardiac muscle isoform, Troponin I type 3 cardiac, troponin I, cardiac 3, TroponinI, Ttroponin I type 3 (cardiac)

Application: WB

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cardiovascular, Developmental Biology, Signal Transduction, Stem Cells

Background: Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).

Concentration: 140 μg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Cardiac Troponin I

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 24 kDa

Molecular Weight(Observed): 28 kDa