TPP1 Antibody (N-term) [APR13781G]

TPP1 Antibody (N-term) [APR13781G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This TPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-34 amino acids from the N-terminal region of human TPP1.

Cellular Localisation: Lysosome. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV

Molecular Weight: 61248

Clone: Polyclonal

Gene Name: TPP1

Gene ID: 1200

Function: Lysosomal serine protease with tripeptidyl-peptidase I activity (PubMed:11054422, PubMed:19038966, PubMed:19038967) . May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases (PubMed:11054422, PubMed:19038966, PubMed:19038967) . Requires substrates with an unsubstituted N-terminus (PubMed:19038966) .

Summary: Tissue Location: Detected in all tissues examined with highest levels in heart and placenta and relatively similar levels in other tissues

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Tripeptidyl-peptidase 1, TPP-1, Cell growth-inhibiting gene 1 protein, Lysosomal pepstatin-insensitive protease, LPIC, Tripeptidyl aminopeptidase, Tripeptidyl-peptidase I, TPP-I, TPP1, CLN2