Description
TPX2 Polyclonal Antibody | E-AB-17129 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: C20ORF1, C20orf2, Chromosome 20 Open Reading Frame 1, Differentially expressed in cancerous and non-cancerous lung cells 2, Differentially expressed in cancerous and noncancerous lung cells 2, Differentially expressed in lung cells 2, Differentially expressed in lung cells, DIL 2, DIL-2, DIL2, FLS353, GD:C20orf1, HCA 519, HCA519, HCTP 4, HCTP4, Hepatocellular carcinoma associated antigen 519, Hepatocellular carcinoma-associated antigen 519, p100, Preferentially expressed in colorectal cancer, Protein fls353, REPP 86, repp86, Restricted expression proliferation associated protein 100, Restricted expression proliferation-associated protein 100, Targeting protein for Xklp2, TPX 2, TPX2, TPX2 microtubule associated homolog, TPX2 microtubule associated protein homolog, TPX2 microtubule nucleation factor, TPX2
Application: WB, ELISA
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Cell biology, Epigenetics and Nuclear Signaling
Background: TPX2 (targeting protein for Xklp2) is a microtubule-associated protein involved in targeting the motor protein Xklp2 to microtubules. Ran-GTP activates TPX2 for the chromatin-induced microbutule assembly during M phase. Aurora-A kinase associates with TPX2 at the spindle apparatus and may regulate TPX2 via phosphorylation during the spindle assembly. TPX2 appears to play a structural role in spindle formation. TPX2 activates Eg2 in a microtubule-dependent manner by stimulating the phosphorylation and kinase activity of Eg2.
Concentration: 0.9 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Fusion protein of human TPX2
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:500-2000, ELISA 1:2000-5000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 86 kDa
Molecular Weight(Observed): N/A