TRAIL/Apo2L, human recombinant | 4354

Human TRAIL (TNF-Related Apoptosis Inducing Ligand), also called Apo2 Ligand (Apo2L), is a cytotoxic protein that activates rapid apoptosis in tumor cells, but not at normal cells. The recombinant human TRAIL/Apo2L is a single polypeptide chain containing 168 amino acids and has a molecular mass of 19.6 kDa.

4354 | TRAIL/Apo2L human recombinant DataSheet

Biomolecule/Target: TRAIL/Apo2L

Synonyms: Tumor necrosis factor ligand superfamily member 10, TNF-related apoptosis-inducing ligand, Protein TRAIL, Apo-2 ligand, Apo-2L, CD253 antigen, TL2, APO2L, TNFSF10.

Alternates names: Stromal-Cell Derived Factor-1, CXCL12, PBSF

Taglines: A ligand molecule which induces apoptosis

NCBI Gene ID #: 24772

NCBI Gene Symbol: SDF-1

Gene Source: RAT

Accession #: Q9QZD1

Recombinant: Yes

Source: E. Coli

Purity by SDS-PAGEs: 95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: HPLC

Endotoxin Level: < 0.1 ng/g of protein (<1EU/g).

Activity (Specifications/test method): Determined by its ability to chemoattract human monocytes using a concentration range of 100.0-200.0 ng/ml.

Biological activity: Determined by its ability to chemoattract human monocytes using a concentration range of 100.0-200.0 ng/ml.

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 8.4 kDa

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Sterile filtered through a 0.2 micron filter. Lyophilized with no additives

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Amino acid sequence: KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKSNNRQVC IDPKLKWIQE YLDKALNKRL KM