TRIM58 Antibody | 8545

TRIM58 Antibody | 8545 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: TRIM58 antibody was raised against a peptide corresponding to 17 amino acids near the carboxy terminus of human TRIM58.

Research Area: Stem Cell

Tested Application: E, WB

Application: TRIM58 antibody can be used for Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human and mouse samples. All other applications and species not yet tested.

Specificiy: N/A

Positive Control 1: Cat. No. 1301 - Human Heart Tissue Lysate

Positive Control 2: Cat. No. 1405 - Mouse Kidney Tissue Lysate

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 53 kDa
Observed: 56 kDa

Validation: N/A

Isoform: N/A

Purification: TRIM58 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: TRIM58 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: TRIM58 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: TRIM58 Antibody: Tripartite motif containing 58 protein, BIA2

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: TRIM58 Antibody: TRIM58 is a member of the tripartite motif-containing family of proteins that frequently possess E3 ubiquitin ligase activities (1) . TRIM58 is strongly expressed in erythroid lineage cells and is further upregulated during late erythroid maturation. Recent experiments suggest that TRIM58 facilitates erythroblast enucleation by ubiquitinating the intermediate chain of the microtubule motor dynein, thereby inducing proteolytic degradation (2) .