TROP2 polyclonal Antibody | BS91376

TROP2 polyclonal Antibody | BS91376 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB ICC IHC

Application Range: WB:1:500-1:2,000 ICC:1:50-1:200 IHC:1:50-1:200

Background: TROP-2, also known as tumor-associated calcium signal transducer 2 (TACSTD2), pancreatic carcinoma marker protein GA733-1, membrane component chromosome 1, surface marker 1 (M1S1) or epithelial glycoprotein-1 (EGP-1), is a cell surface glycoprotein receptor. It is a single pass type I membrane protein containing one thryoglobulin type-1 domain, an epidermal growth factor-like repeat, a phosphatidylinositol binding site and tyrosine phosphorylation sites near the C-terminus. TROP-2 plays a role in tranducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multistratified epithelia. It is also highly expressed in several types of tumors and is involved in regulating the growth of carcinoma cells. Mutations in the gene encoding TROP-2 can result in gelatinous drop-like corneal dystrophy (GDLD) also referred to as lattice corneal dystrophy type III, an autosomal recessive disorder that causes severe visual impairment.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Specificity: TROP2 polyclonal Antibody detects endogenous levels of TROP2 protein.

Molecular Weight: 35 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: TACSTD2, GA733-1, M1S1, TROP2, Cell surface glycoprotein Trop 2, Cell surface glycoprotein Trop-2, Cell surface glycoprotein Trop2, Epithelial glycoprotein 1, GA733 1, GA7331, M1S 1, M1S1, Membrane component chromosome 1 surface marker 1, Pancreatic carcinoma marker protein GA733 1, Pancreatic carcinoma marker protein GA733-1, Pancreatic carcinoma marker protein GA7331, TACD 2, TACD2, TACSTD 2, Tacstd2, Trop 2, Trop2, Tumor associated calcium signal transducer 2 precursor, Tumor-associated calcium signal transducer 2,

Immunogen: Recombinant protein.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Protein affinity purified.

Pathway: