Troponin I3 (phospho-S22/S23) polyclonal Antibody | BS4281

Troponin I3 (phospho-S22/S23) polyclonal Antibody | BS4281 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: Troponin I is part of a heteromeric complex playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, troponin I (TnI), troponin T (TnT) and troponin C (TnC) . Each subunit is responsible for part of troponin complex function. TnI inhibits ATPase activity of acto myosin and TnT and TnI are present in cardiac muscles in different forms than in skeletal muscles. Only one tissue specific isoform of TnI is described for cardiac muscle tissue (cTnI) and this is expressed only in myocardium.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Troponin I3 (phospho-S22/S23) polyclonal antibod detects endogenous levels of Troponin I3 protein only when phosphorylated at Ser22 and Ser23.

Molecular Weight: ~ 28 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Troponin I, cardiac muscle; Cardiac troponin I; TNNI3; TNNC1

Immunogen: Synthetic phosphopeptide derived from human Troponin I3 around the phosphorylation site of Ser22/23.

Conjugate: Unconjugated

Modification: Phosphorylation

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: