TRPC4AP Polyclonal Antibody | E-AB-17161

TRPC4AP Polyclonal Antibody | E-AB-17161 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: C20orf188, TRPC4AP, Chromosome 20 open reading frame 188, Protein TAP1, Protein TRUSS, Short transient receptor potential channel 4 associated protein, Short transient receptor potential channel 4-associated protein, TAP1 protein, TNF receptor ubiquitous scaffolding/signaling protein, TNF-receptor ubiquitous scaffolding/signaling protein, TP4AP, Transient receptor potential cation channel, subfamily C, member 4 associated protein, Trp4 associated protein, Trp4-associated protein, Trpc4 associated protein, Trpc4-associated protein, TRPC4AP, TRRP4AP, TRUSS, Tumor necrosis factor receptor-associated ubiquitous scaffolding and signaling protein

Application: IHC, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Epigenetics and Nuclear Signaling, Signal transduction

Background: TRPC4AP (transient receptor potential cation channel, subfamily C, member 4 associated protein), also known as TRUSS or TRRP4AP, is a 797 amino acid protein that is expressed in a variety of tissues, with highest expression in liver, heart, testis and brain. Thought to function as a scaffolding protein, TRPC4AP interacts with TNF-R1 and may both link TNF-R1 to the IKK signalsome complex, and participate in the activation of NFκB p50, an event that occurs in response to TNF-R1 ligation. TRPC4AP exists as multiple alternatively spliced isoforms that are encoded by a gene whicHuman, Mouseaps to human chromosome 20. Comprising approximately 2% of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome.

Concentration: 0.9 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human TRPC4AP

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:30-150, ELISA 1:2000-10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A