TRPC5 polyclonal Antibody | BS70974

TRPC5 polyclonal Antibody | BS70974 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Rat

Application: WB IHC

Application Range: WB 1:500 - 1:2000 IHC 1:50 - 1:200

Background: Human TRP1 protein is a 793 amino acid cation channel that is expressed in fetal and adult brain and in adult heart, testis and ovary, where it may influence store-operated Ca2+ entry as a component of capacitative calcium entry (CCE) complexes. The brain-specific subunit TRP5 forms a nonselective cation channel with TRP1 in the hippocampus that is activated by Gq-coupled receptors, but not by depletion of intracellular Ca2+ stores. The gene encoding human TRP5 maps to chromosome Xp23, which also contains loci for nonsyndromic mental retardation and X-linked disorders.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: TRPC5 polyclonal Antibody detects endogenous levels of TRPC5 protein.

Molecular Weight: ~ 111 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Short transient receptor potential channel 5; TrpC5; Transient receptor protein 5; TRP-5; hTRP-5; hTRP5; TRPC5; TRP5

Immunogen: Recombinant protein of human TRPC5.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Vesicle Trafficking presynaptic signaling,Adherens Junction signaling,